KPV

KPV is a tripeptide consisting of the residues lysine-proline-valine, corresponding to the C-terminal fragment of the alpha-melanocyte-stimulating hormone (α-MSH) sequence. It is registered under CAS 131180-41-1 with the molecular formula C₁₆H₂₉N₅O₅ and a reported mass of approximately 371.4 Da. As one of the smallest peptides in the catalog, it is a fully defined synthetic sequence that is reproducible from lot to lot, and it is supplied solely as a research-grade material for qualified laboratory use.

KPV is manufactured by solid-phase peptide synthesis and presented as a white lyophilized powder in a 10mg presentation. As a small three-residue peptide it dissolves readily in water-based research preparations, and the freeze-dried format supports stable storage and straightforward handling in a laboratory environment. The compact size of the molecule makes reconstitution quick and predictable when a working solution is prepared for a bench protocol. Because a low-mass peptide of about 371 Da corresponds to a relatively large molar amount per milligram, researchers typically calculate working concentrations with particular care. KPV dissolves quickly and completely in a neutral aqueous solvent with only gentle mixing, and recording the reconstitution date alongside the lot identifier provides a clear reference for the age of any prepared solution used at the bench.

Each lot is characterized analytically using two complementary techniques. Reverse-phase HPLC resolves the tripeptide from synthesis-related impurities using a solvent gradient, presenting it as a single dominant peak under UV detection so that chromatographic purity can be evaluated. LC-MS confirms molecular identity by matching the measured mass to the theoretical value for the sequence. As a low-mass three-residue peptide, its expected mass is precisely defined, and the agreement between measured and theoretical values gives a clear identity check for each lot.

For research handling, the lyophilized powder is stored at -20 °C and protected from light. Once reconstituted with a solvent appropriate to the protocol, solutions are commonly divided into aliquots and kept cold to reduce freeze–thaw exposure, which helps maintain a stable analytical reference. The choice of solvent, working concentration, and handling parameters is left to the researcher and the requirements of the specific experiment.

Every order includes lot-traceable documentation — Certificate of Analysis, RP-HPLC purity report, and independent third-party report — tied to a verifiable lot identifier that can be checked before use. KPV is supplied for laboratory research use only and is not intended for human consumption, therapeutic use, diagnostic use, or veterinary use. No medical or health claims are made about this material.