Ipamorelin

Ipamorelin is a synthetic pentapeptide — a five-amino-acid chain described in the scientific literature as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a), the ghrelin receptor. It carries the CAS registry number 170851-70-4 and the molecular formula C₃₈H₄₉N₉O₅, with a reported mass of approximately 711.9 Da. As a fully defined synthetic sequence rather than an extract, it is reproducible from lot to lot, and it is supplied strictly as a research material for in-vitro laboratory work by qualified professionals within the Growth Factors research category.

Each batch is manufactured by solid-phase peptide synthesis (SPPS), in which the chain is assembled one residue at a time on a solid support before cleavage and purification, and it is presented as a white lyophilized (freeze-dried) powder. The sequence incorporates non-natural residues and a C-terminal amide — structural features described in the literature as contributing to the molecule's stability — and as a compact five-residue peptide it dissolves readily in water-based research preparations when a working solution is prepared for a bench protocol. Lyophilization removes water from the purified material, which improves shelf stability, simplifies cold-chain shipping, and supports consistent handling at the bench. The material in this listing is offered in a 10mg presentation intended for analytical and in-vitro research applications, and researchers frequently record the reconstitution date alongside the lot identifier so that the age of a working solution can be tracked against the analytical reference on its Certificate of Analysis.

Identity and purity are characterized for every lot using two complementary analytical methods. Purity is assessed by reverse-phase high-performance liquid chromatography (RP-HPLC), which uses a solvent gradient to separate the target peptide from synthesis-related impurities and resolves it as a single dominant chromatographic peak detected by UV absorbance. Identity is confirmed by liquid chromatography–mass spectrometry (LC-MS), which measures the molecular mass and compares it against the theoretical mass calculated from the sequence. Because the two techniques probe different properties — chromatographic behavior and molecular mass — they provide orthogonal confirmation that the material matches its specification.

For research handling, the lyophilized powder should be stored at -20 °C and protected from light. Once a stock is reconstituted with an aqueous solvent appropriate to the protocol, peptide solutions are generally divided into single-use aliquots to limit repeated freeze–thaw cycles, which helps preserve a stable analytical reference between measurements. Reconstitution solvent, working concentration, and storage of the prepared solution are determined by the researcher according to the requirements of the specific experiment.

Every order ships with lot-traceable documentation: a Certificate of Analysis recording the lot-specific purity, mass confirmation, and release date, together with the RP-HPLC purity report and the independent third-party report. The unique lot identifier ties all of these records to the physical material, so researchers can verify the lot against its documentation before use. Ipamorelin is supplied for laboratory research use only — it is not a drug, food, cosmetic, or dietary supplement, and it is not intended for human consumption, therapeutic use, diagnostic use, or veterinary use.